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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68eec8e6b88175b05d5f1e20be9fb07cba3fb9972750a889785e77027189c979' 
  AND token = 'VJke6+DV2dp+RaJsGrTgzNFLub2wdu1IzzDG6EyCmwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}