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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2256f2fdd58277ffff5499eec615d50a9554e059d73a1029a6bd26900cd21f38' 
  AND token = 'ETtwGLY636qrjZTSsuVYlDdce5wzH6qLTL8GYMfFdak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}