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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c983f72c015478ee2e93e0e60a654ebc968b1be6b7c8edbbc7d8b21a9ca3514d' 
  AND token = 'tUu+1P6sZoE7hKTLqgBKLkx4dxxH4LowGCeNwV8lW1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}