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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac92649f9221c3ecd209a0ed513db5a164a3135da767e81690942242419584d' 
  AND token = 'zbmb+zxeadupGeVYVY1EVR2lFO6twK6LzNeHQ1bzUbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}