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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a931fa13fe67cb7294cd35ab52a813e149d55d5a013ed21c3b143ca2b5bd192' 
  AND token = 'rEagI0G4xAX0ZrrLqRjKcPzi6buD1Y/VvD/fMX4b0Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}