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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00b78302f138d1fa245f835835e16146e275c60c77af3483031e7e267666c72' 
  AND token = '3kjknfBKsMbiuX+ZmRt40z/3EqcyQ7ECqvKvHS/OrJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}