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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75eff1086736d24b0a19710e2db0c175305ace77f9496c4ac3e3311e0d726156' 
  AND token = '5/Uh2S0jbbF5loh8SXinPUmhy3nzJpR7fwUM9VoDE7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}