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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df0bf40220c5243fb4d28d7a46b87354dd6b023446dd0483452af7e2676781e' 
  AND token = '3PJ7SJmlnHD1gyA1JZDEWlTOjEe07FnKjwB3iu/KEGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}