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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9714688ffc9da5d4039fd29f3455b02c1141f4a6b94808cf0f9210ad62fe6a8' 
  AND token = 'C65JnRy8U1HlTnI2UYRhJAFltZ3nUPEMtGtEFxdMcQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}