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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dca781f70c98e4f83dcd245e1797eb0881149ccaf2610c55b29b7101e321a85' 
  AND token = 'y6mYGFh8hGszFpHN95qu853+ZG6vO0siIemnNWjle2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}