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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c3b960680c69eea6f9e794e7f946fa4b3526a153915a3d4f6d2bf96c247de5' 
  AND token = '+fdyWPFw6f3izGbV21XqdbuBGE153jglP/o23oXbx60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}