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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1067416eee7dab9d0fe376083090a6c8e70e8f50dd61b7af59cdb02998c20cb0' 
  AND token = 'ZT5iFfqnfQxR0TBJSQycnm8eRfRuc1WbViDuoKZ5/Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}