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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7499bd0e65e1a357a440fc28b321604576a666ddc6dd30649cf666654580116' 
  AND token = '0qn6Sk2OdefE+trS4awPUyGw807qIjSpG5JWjBRPAB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}