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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887508d1b4d5d0ade1a50adf79b03bfefcb1a0ec3d8b0b6a516c3705e19ff666' 
  AND token = 'wlNaYOUTRpVAk7b1X8qxWjYPrKASmjG6bh5GKuF5Ya0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}