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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7fb3caaf004bcbd864c46637b27a4fb79f3d9c3d8177fc7481cbd0bb1f8237' 
  AND token = 'n0vYHs+26sWJqxIELGLJL68kopH8m8gmiTkSKtvpUwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}