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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c603a2a61928fa1e062be2d6f457e6412b87b48aa0c846309f5095a3aed7cbdd' 
  AND token = 'HNLPgbv5vqLId/nCRpK012SNFpmi3SaoGj2EJHbj8Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}