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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf2ec8e3cbc83e1c6f6a0d0c408103269d926f3023ba45248e90b4f7ad1610b' 
  AND token = 'KToSiYFpEt9KUhLB3uMQWilXbI3iTfH91VYa0qQf428=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}