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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73b35c3edbc6db31e7283e5fbf0b9759d635b3d2210bc366a1e42bcc341b1985' 
  AND token = 'JTFMDya1Jw3/NpY10WGn+kKAH6xxr+9AXAPaNHlugqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}