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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33cd472ad35d110c09bb04ce6de162d4497405481f73973e691194aa0d42fdc' 
  AND token = 'cq4v8bW8LJUYL7a9BtrKzLb7A4k68yURnsDDJDJzmZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}