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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c659b600ae9d058679175c81d729d6d72118f6eee6f01edf0bccb2d64f8a9475' 
  AND token = 'IPp0OkNLd6hJh2Krnei6YaNAkCEm0JYh0ZLmpE7L3K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}