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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a9cc5969ab1c40fe6f24da043fc6f22997e0a30a6a337ca8839d1b54824800' 
  AND token = 'bJ9qTI89hpKN8ujFzEGKmT5VjNA8OaQpsUxouTyEpr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}