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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335a38e64eb24ae5bc1f5d93937485a5d0573fb4c7bebcb3a3d0ae6b10f62344' 
  AND token = 'TXNVB3zATMbm0pfGNL0oT6agSQ/ymSbUpbJjDEPo3ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}