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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9246c19ee4b2963369ff43d1aabd34e9e8a3435e2293747e5905988c93d3a5c' 
  AND token = 'bevFPL/d1YD1TrMayA11rGOkfJS6klVr7YpUZG8Ou5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}