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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3301a6102ab4f609f2ee1127f32a58165519206c20d11830049decb0714b659' 
  AND token = 'ssKDEVbOOudHt8NBPG6KCUdq5HSPiKogZbhr6w2XHwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}