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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '317dcd9c12ccbf36da7cabd576648755b9e67d9c91a1439dafeebcf187cf1ce3' 
  AND token = 'bE5lGfGld/LYSkkK/Xvqy6wtqRVEpaD6q5gm3gbABHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}