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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e99da7f48f6620a04a493e59c6173f1fd14ccfe76c6993073a17345d81f2c9' 
  AND token = 'bH2Jo6RMYIpdeT2pRGR0Wzy4wPNHInfXhbtGfvbXirA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}