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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0606ee25276dc3852de7e5f84d801eeff885d033b89641699ebb3eed9a3e713c' 
  AND token = '+HHn1qm3trUh15NxaG2kKBr7CyKAoF8CRWm3b1XkoH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}