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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fab6a6fc4117f693480180370072ca5c0e7b19fc35a018ff7cd7b18b3dc3e7a' 
  AND token = 'uA0pe+kpCXyI+zU0xON5L9yNw66r+Pk8JUn8gQR+tbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}