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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd11e23900d6c272b4e1a7cbd0c6acc993a4de641dfc24944e934dff902e0bd' 
  AND token = 'Cuuy16DihukyWl4FviLldpl17BlpWtz5Vy9XaXK3ubI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}