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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f12b39206ab42e9e2c89cc4dfebe5c62e8fc468d6bb249e6a6e667db9685e532' 
  AND token = 'HoZua0ojoKM7RDtY1rkg9wefJwETOUntXR4G7O+Aghc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}