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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f18d772c01a8a36f98c65a7bdd21ec2c01de16d8f00f2f6a9c7569fc570cbf5' 
  AND token = 'O/7n3XsF8bXf/kB+Qsl3vfuB4GJKKCiM1sIy4RKcXKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}