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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4783e06e0c68c87d4f3d0a583b30d3953e275a21cb35235fa270bddaa656b0d' 
  AND token = '2cdietm2k6B2X+AEjI4m9pk3Qxdq4++MTN/cWNhU2Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}