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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9412ec56a4147cc3f80f0a8cb1563620c16908e9c498a62cafe8a17c07de933f' 
  AND token = 'tJKrRJCxC+kDLjL/aiid3T6OWnmPKjevq0/3UhVMee0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}