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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '835fe29830443dde483afef0bc25137d48dd8933b4cc9bc842834cace4a72e08' 
  AND token = 'M7Z/8IWVMOG6MGl9hgKGoua10iU3OLLbY3UpGXf8lYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}