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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b0c0f199af2d4d36af70d3556dd042c1ae485b2e10d793847980872378695e1' 
  AND token = '+2aqRk1+iwQny+vXf7cDOl8GkBtoFJ8PGAd9+nYUaWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}