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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6021d4475c570f662c622b7a4f4072dad4ae08076d6044ee12331087858fa900' 
  AND token = 'ZxS+Kt0pcB1Bl+Mpao8kRiCDvxtbKtgrl79l6/IQG7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}