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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b30382d44c615545a3ceef64f71806ef696000b0ffb117d0aeea777f436fc779' 
  AND token = 'O6BjA+MFFk4tt+ubOmz+KCFp9EkuT2HqJfT9Rixd5tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}