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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd55b5f588a3f57b481c424700e83133e51aa1f76f98c3b59f62b81a3822a53a3' 
  AND token = 'Et541V5ih+5Z7idwPQex0cwXprdmPYzYvoQPqTvcLA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}