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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72deec16a946fccb90cb7cc778063be92bc4ec9b82607d93773f397d04d7b73' 
  AND token = 'vEZ+rREmfGju9jrkzTZSn3C1fLKguyhZN+WX1W4yYX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}