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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8356a835ebab08ca7758d475e4df61bd8c8d2f298df717658a76099b2c929fcd' 
  AND token = '+c2uNd5A5c/oaWDxTHPGc3LQiwbLv2mu10XBCthtKlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}