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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8721da1bd0fcc180fc3c1248ba471cbe9e6fafc873666e349e3403b12f221734' 
  AND token = 'RnctX83GE6Dfv/BebXV6K478qGHrr2Fm2T1wNcbVsf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}