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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c54fc4ed7f4e92449a460a7e224aa29d5e0648d96d08cd3f2de47fa0ad9d2b5' 
  AND token = 'Vpdo+dQfA7s85prv+85A7/Jc2CFc5i8WQXC2jOi8dsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}