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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c5d09fa2a58f835e5c87483f1dd47d471c6a43f8dc98d09899595995cd2ed0' 
  AND token = 'CEHUDdEuNETjs14jX/24BsAAOhU8u/R1m0SVG4RRjfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}