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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ade2c17d7df49ea94f4fe9c1d6a11ed09cc382b3a924b97bed48d6c109a50f7' 
  AND token = 'WaNMqgL25/m8nAXA+xS19bs9LA4TUbPnRIizXGOY01U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}