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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b850bf93beabb0972c4e4174a0cc1214fc4bef0d48725ff6cf1d18ead6a0b7c' 
  AND token = '/Ngj5gnAh/X2dxY5ijY3g3IN6cVWxphy+fv5K8l8UY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}