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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd38f0260c36c7dc46e359e7fb92c098e3ce557c64d302f76b988bb3cd987820c' 
  AND token = 'vY/UjFdw5vNviVRCRqoAQEaU6Bgo+pTYfKX+e6Nd9V8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}