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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4fddbb573f734fd184e9f75f9c2a72fb312dd2f54bd63af6ae2a1f07036f7e' 
  AND token = 'LMxJnG3DjZkUG1l6UBnY6jOA4/RlON3QLcXkcDs9eEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}