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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aae3c6a7680cfe27ad75584a09717d1e9cc2ad0d0d495e860d3bc45e4d762a54' 
  AND token = 'nzHx4cUU/8mqy6IF8cpfbp8cL+SnuZ7wKWjg9ppuwLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}