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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26add19c81f623a7698dfe38d0683d3a44f3a94552f3a85386f3ac4125e7623c' 
  AND token = '++xrhfTcTVUs5brx8iDRjZW7uqH+KF3iGzM9S+vY3a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}