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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '826e8029a86ed839324cbad2e881f831a22326e05f2469d3ded99bb423d31c12' 
  AND token = 'yJJTTz9uG5mFm41wAM5UhHAk+iB8hOLtb6tU3LQF8SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}